Fatigue Medicentres

Feeling tired? If so, it’s not surprising, By Dr. Fatemeh Aghanasiri

Fatigue occurs most often as part of a symptom complex, but even when it is the sole or main presenting symptom, fatigue is one of the most common symptoms. Fatigue is difficulty initiating and sustaining activity due to a lack of energy and accompanied by a desire to rest. Fatigue is normal after physical exertion, prolonged stress, and sleep deprivation.

Fatigue is a desire to rest that reflects exhaustion. It differs from weakness, inability to move, and reluctance to move because of pain with movement. Fatigue may reflect activity of a systemic inflammatory disorder.

The most common disorders manifesting predominantly as recent fatigue (lasting lest than 1 month) are

  • Drug adverse effects
  • Anemia
  • Stress and/or depression

The most common causes manifesting predominantly as prolonged fatigue (lasting 1 to 6 months) are

  • Diabetes
  • Hypothyroidism
  • Sleep disturbances (eg, sleep apnea)
  • Cancer

The most common causes manifesting predominantly as chronic fatigue (lasting more than 6 months) are

  • Chronic fatigue syndrome
  • Mood changes (eg, depression)
  • Drugs
  • Chronic weight loss
  • Chronic fever or night sweating
  • Generalized lymphadenopathy
  • Muscle weakness or pain
  • Serious non-fatigue symptoms (blood loss, Sever breathing problem, liver diseases , change of level of conciousness, suicidal ideation)
  • Involvement of more than 1 organ system (eg, skin rashes plus joints pain)
  • New or different headache or loss of vision, particularly with muscle pains, in an older adult
  • Older age (eg, > 65 yr)

By  Dr. Fatemeh Aghanasiri, MD (MCC)

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